Pain in children with sickle cell disease, because it will recur more often than not, must be treated quickly and effectively. Repeated pain, by the way it is experienced, will have an impact on the psychological and physical development of the child and on the way he feels the painful crises that will occur again and again.
In general, the term sickle cell disease is used to describe a group of genetic blood abnormalities of the red blood cells characterized by a predominance of hemoglobin S. The main manifestations of the disease are chronic anemia and organ damage caused by the obstruction. blood flow.
Sickle cell anemia is a chronic disease that poses a major challenge to the medical profession. Frequent hospitalizations can lead to social isolation as well as a child’s failure at school. Sickle cell anemia is in fact a disease of the genes of hemoglobin, a blood protein used to fix and transport respiratory gases in the blood (oxygen and carbon dioxide).
In people with sickle cell anemia, the red blood cells that contain sickle hemoglobin become rigid, elongated, and shaped like a sickle. Thus, they can hardly circulate in the small blood vessels.
Due to the stiffness and shape of sickle red blood cells, blood flow obstruction automatically occurs. It is a non-contagious genetic disease. It is hereditary autosomal, that is to say that it affects both girls and boys, and that it manifests only when one carries two genes for the disease.
Sickle cell disease is more prevalent than any other genetic disease, such as Cystic Fibrosis, Phenylketonuria (PKU), Hemophilia, Tay-Sachs, and Muscular Dystrophy.